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Article

Activating Telomerase TERT Promoter Mutations and Their Application for the Detection of Bladder Cancer.

International journal of molecular sciences - 21 Aug 2020

Zvereva Maria, Pisarev Eduard, Hosen Ismail, Kisil Olga, Matskeplishvili Simon, Kubareva Elena, Kamalov David, Tivtikyan Alexander, Manel Arnaud, Vian Emmanuel, Kamalov Armais, Ecke Thorsten, Calvez-Kelm Florence Le

Abstract excerpt

This review summarizes state-of-the-art knowledge in early-generation and novel urine biomarkers targeting the telomerase pathway for the detection and follow-up of bladder cancer (BC). The limitations of the assays detecting telomerase reactivation are discussed and the potential of transcription-activating mutations in the promoter of the TERT gene detected in the urine as promising simple non-invasive BC...

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Identifiers

PMID: 32839402
DOI: 10.3390/ijms21176034
PMCID: PMC7503716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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