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Article

Risk-reducing mastectomy for the prevention of primary breast cancer.

The Cochrane database of systematic reviews - 5 Apr 2018

Carbine Nora E, Lostumbo Liz, Wallace Judi, Ko Henry

Abstract excerpt

BACKGROUND: Recent progress in understanding the genetic basis of breast cancer and widely publicized reports of celebrities undergoing risk-reducing mastectomy (RRM) have increased interest in RRM as a method of preventing breast cancer. This is an update of a Cochrane Review first published in 2004 and previously updated in 2006 and 2010. OBJECTIVES: (i) To determine whether risk-reducing mastectomy reduces...

Topics

Breast Neoplasms
Female
Genes, BRCA1
Genes, BRCA2
Genetic Predisposition to Disease
Humans
Observational Studies as Topic
Patient Satisfaction
Postoperative Complications
Prophylactic Mastectomy
Risk Assessment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Unilateral Breast Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 29620792
DOI: 10.1002/14651858.CD002748.pub4
PMCID: PMC6494635

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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