Article
Bilateral Prophylactic Nipple-Sparing Mastectomy: Analysis of the Risk-Reducing Effect in BRCA1/2 Mutation Carriers.
Aesthetic plastic surgery - 1 Apr 2022
Stanek Krystof, Zimovjanova Martina, Suk Petr, Jonas Filip, Zimovjanova Anna, Molitor Martin, Mestak Ondrej
Abstract excerpt
BACKGROUND: Mutations in the BRCA1 or BRCA2 genes increase the lifetime risk of developing breast cancer to 68-72% by the age of 80. One of the modalities to manage the risk is a prophylactic mastectomy. Bilateral nipple-sparing mastectomy specifically offers the most favorable esthetic outcomes but the evidence for its oncological safety remains limited. Thus, we aimed to compare the occurrence of breast cancer...
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