Article
Lethal(2)giant larvae is required in the follicle cells for formation of the initial AP asymmetry and the oocyte polarity during Drosophila oogenesis.
Cell research - 1 Mar 2008
Li Qi, Xin Tianchi, Chen Wenlian, Zhu Mingwei, Li Mingfa
Abstract excerpt
The intricately regulated differentiation of the somatic follicle cell lineages into distinct subpopulations with specific functions plays an essential role in Drosophila egg development. At early oogenesis, induction of the stalk cells generates the first anteroposterior (AP) asymmetry in the egg chamber by inducing the posterior localization of the oocyte. Later, the properly specified posterior follicle cells...
Topics
- Animals
- Cell Polarity
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Male
- Mutation
- Oocytes
- Oogenesis
- Ovarian Follicle
- Tumor Suppressor Proteins
