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Article

Product Formation by the Promiscuous Lanthipeptide Synthetase ProcM is under Kinetic Control.

Journal of the American Chemical Society - 22 Apr 2015

Yu Yi, Mukherjee Subha, van der Donk Wilfred A

Abstract excerpt

Lanthipeptides are natural products that belong to the family of ribosomally synthesized and post-translationally modified peptides (RiPPs). They contain characteristic lanthionine (Lan) or methyllanthionine (MeLan) structures that contribute to their diverse biological activities. Despite its structurally diverse set of 30 substrates, the highly substrate-tolerant lanthipeptide synthetase ProcM is shown to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25803126
DOI: 10.1021/jacs.5b01409
PMCID: PMC4487812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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