Article
Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides.
Proceedings of the National Academy of Sciences of the United States of America - 14 Sept 2010
Claesen Jan, Bibb Mervyn
Abstract excerpt
Posttranslational modification of amino acids confers a range of structural features and activities on ribosomally synthesized peptides, many of which have potent antimicrobial or other biological activities. Cypemycin is an extensively modified linear peptide produced by Streptomyces sp. OH-4156...
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