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Prevalence of CYP2C19 alleles, pharmacokinetic and pharmacodynamic variation of clopidogrel and prasugrel in Bangladeshi population.

Clinical and experimental pharmacology & physiology - 1 May 2015

Bin Sayeed Muhammad Shahdaat, Hasan Apu Mohd Nazmul, Munir Maliha Tabassum, Ahmed Maizbha Uddin, Islam Mohammad Safiqul, Haq M Maksumul, Ahsan Chowdhury H, Rashid M A, Shin Jae Gook, Hasnat Abul

Abstract excerpt

The extent to which cytochrome P450 (CYP) 2C19 genotype influences the effectiveness of clopidogrel remains uncertain due to considerable heterogeneity between studies. We used the polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method for genotyping loss of function (LOF) allele, CYP2C19*2 and gain of function (GOF) allele, CYP2C19*17 in 163 patients undergoing PCI and 165 healthy...

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Identifiers

PMID: 25800075
DOI: 10.1111/1440-1681.12390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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