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Article

Prevalence and types of genetic polymorphisms of CYP2C19 and their effects on platelet aggregation inhibition by clopidogrel.

European review for medical and pharmacological sciences - 1 Nov 2020

Aga Q A A, Hasan M K, Nassir K F, Aga L A A, Al-Jaidi B A, Aldhoun M, Morsy M A, Nair A B

Abstract excerpt

OBJECTIVE: The current study was conducted to determine the distribution of genetic polymorphisms in CYP2C19 in Iraqi patients and their role in inter-individual variability of clopidogrel efficacy. PATIENTS AND METHODS: A prospective controlled study was done on 100 patients under high risk of cardiovascular diseases who started clopidogrel prophylactic therapy. Polymerase chain reaction-restriction fragment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33215448
DOI: 10.26355/eurrev_202011_23618

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