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Article

Polymorphisms of MDR1, CYP2C19 and P2Y12 genes in Indian population: effects on clopidogrel response.

Indian heart journal - 1 Jan 2000

Shalia Kavita K, Shah Vinod K, Pawar Poonam, Divekar Siddhi S, Payannavar Satchidanand

Abstract excerpt

AIMS/OBJECTIVE: Influence of genetic variations on the response of clopidogrel, an antiplatelet drug is implicated. In the present study, the prevalence of single nucleotide polymorphisms of MDR1 (C3435T), CYP2C19 [CYP2C19*2 CYP2C19*3, CYP2C19*17] and P2Y12 (i-T744C) in Indian population and their effects on clopidogrel response was analyzed. METHODS AND RESULTS: To analyze the prevalence of polymorphisms, 102...

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ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1
Clopidogrel
Cytochrome P-450 CYP2C19
Platelet Aggregation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Platelet Aggregation Inhibitors

Receptors, Purinergic P2Y12

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Identifiers

PMID: 23647895
DOI: 10.1016/j.ihj.2013.02.012
PMCID: PMC3861302

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