Article
DNA template dependent accuracy variation of nucleotide selection in transcription.
PloS one - 1 Jan 2015
Mellenius Harriet, Ehrenberg Måns
Abstract excerpt
It has been commonly assumed that the effect of erroneous transcription of DNA genes into messenger RNAs on peptide sequence errors are masked by much more frequent errors of mRNA translation to protein. We present a theoretical model of transcriptional accuracy. It uses experimentally estimated standard free energies of double-stranded DNA and RNA/DNA hybrids and predicts a DNA template dependent transcriptional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
