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Article

Altering the substrate specificity of methyl parathion hydrolase with directed evolution.

Archives of biochemistry and biophysics - 1 May 2015

Ng Tee-Kheang, Gahan Lawrence R, Schenk Gerhard, Ollis David L

Abstract excerpt

Many organophosphates (OPs) are used as pesticides in agriculture. They pose a severe health hazard due to their inhibitory effect on acetylcholinesterase. Therefore, detoxification of water and soil contaminated by OPs is important. Metalloenzymes such as methyl parathion hydrolase (MPH) from Ps...

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Identifiers

PMID: 25797441
DOI: 10.1016/j.abb.2015.03.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25797441-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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