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Article

High-throughput screening system based on phenolics-responsive transcription activator for directed evolution of organophosphate-degrading enzymes.

Protein engineering, design & selection : PEDS - 1 Nov 2012

Jeong Young-Su, Choi Su-Lim, Kyeong Hyun-Ho, Kim Jin-Hyun, Kim Eui-Joong, Pan Jae-Gu, Rha Eugene, Song Jae Jun, Lee Seung-Goo, Kim Hak-Sung

Abstract excerpt

Synthetic organophosphates (OPs) have been used as nerve agents and pesticides due to their extreme toxicity and have caused serious environmental and human health problems. Hence, effective methods for detoxification and decontamination of OPs are of great significance. Here we constructed and used a high-throughput screening (HTS) system that was based on phenolics-responsive transcription activator for...

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PMID: 23077277
DOI: 10.1093/protein/gzs071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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