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CYP2J2 rs890293 polymorphism is associated with susceptibility to Alzheimer's disease in the Chinese Han population.

Neuroscience letters - 23 Apr 2015

Yan Huacheng, Kong Yanying, He Baoxia, Huang Mukun, Li Jian, Zheng Jiaqiang, Liang Lei, Bi Jianjun, Zhao Shujin, Shi Lei

Abstract excerpt

Alzheimer's disease (AD) is a common neurodegenerative disorder characterized by progressive cognitive dysfunction and memory loss. Increasing evidence indicates that inflammation in the brain is a powerful factor in AD progression. Epoxyeicosatrienoic acids, the biologically active derivatives of arachidonic acid, synthesized by cytochrome P450 (CYP) epoxygenases, have been proven to have powerful...

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PMID: 25796175
DOI: 10.1016/j.neulet.2015.03.024

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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