Article
Gene- gene interaction between CYP2J2 and PPAR -γ gene on late-onset Alzheimer's disease in the eastern Chinese Han population.
Behavioural brain research - 30 Mar 2017
Geng Shuang, Wang Yutong, Sun Yongmei, Li Jinfeng, Yin Honglei, Zeng Zhilei, Yang Xiaopeng, Zhang Yuzhen, Wang Yunliang
Abstract excerpt
AIMS: To investigate the impact of PPAR -γ and CYP2J2 gene single nucleotide polymorphisms (SNPs) and gene- gene interactions on late-onset Alzheimer's disease (LOAD) risk in Chinese Han population. METHODS: A total of 880 participants (514 males, 366 females), with a mean age of 81.7±15.9years old are selected, including 430 LOAD patients and 450 normal participants. Generalized multifactor dimensionality...
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