Article
Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma.
PloS one - 1 Jan 2015
Chen Jingyan, Tibroni Nadine, Sauter Daniel, Galaski Johanna, Miura Toshiyuki, Alter Galit, Mueller Birthe, Haller Claudia, Walker Bruce D, Kirchhoff Frank, Brumme Zabrina L, Ueno Takamasa, Fackler Oliver T
Abstract excerpt
In the absence of antiretroviral therapy, infection with human immunodeficiency virus type 1 (HIV-1) can typically not be controlled by the infected host and results in the development of acquired immunodeficiency. In rare cases, however, patients spontaneously control HIV-1 replication. Mechanisms by which such elite controllers (ECs) achieve control of HIV-1 replication include particularly efficient immune...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.