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Article

Viral Characteristics Associated with the Clinical Nonprogressor Phenotype Are Inherited by Viruses from a Cluster of HIV-1 Elite Controllers.

mBio - 10 Apr 2018

Casado Concepción, Marrero-Hernández Sara, Márquez-Arce Daniel, Pernas María, Marfil Sílvia, Borràs-Grañana Ferran, Olivares Isabel, Cabrera-Rodríguez Romina, Valera María-Soledad, de Armas-Rillo Laura, Lemey Philippe, Blanco Julià, Valenzuela-Fernández Agustín, Lopez-Galíndez Cecilio

Abstract excerpt

A small group of HIV-1-infected individuals, called long-term nonprogressors (LTNPs), and in particular a subgroup of LTNPs, elite controllers (LTNP-ECs), display permanent control of viral replication and lack of clinical progression. This control is the result of a complex interaction of host, immune, and viral factors. We identified, by phylogenetic analysis, a cluster of LTNP-ECs infected with very similar...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to env Gene Products, Human Immunodeficiency Virus

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Identifiers

PMID: 29636433
DOI: 10.1128/mBio.02338-17
PMCID: PMC5893881

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