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Article

DRD3 gene and striatum in autism spectrum disorder.

The British journal of psychiatry : the journal of mental science - 1 May 2015

Staal Wouter G, Langen Marieke, van Dijk Sarai, Mensen Vincent T, Durston Sarah

Abstract excerpt

A single-nucleotide polymorphism (SNP) of the DRD3 gene (rs167771) was recently associated with autism spectrum disorders (ASD). Different polymorphisms of rs167771 corresponded to varying degrees of stereotyped behaviour. As DRD3 receptors are relatively overexpressed in the striatum, we investigated whether striatal volume was related to these polymorphisms in autism. We assessed volumes of caudate nucleus and...

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Identifiers

PMID: 25792691
DOI: 10.1192/bjp.bp.114.148973

Genes

DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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