Article
A common variant in DRD3 receptor is associated with autism spectrum disorder.
Biological psychiatry - 1 Apr 2009
de Krom Mariken, Staal Wouter G, Ophoff Roel A, Hendriks Judith, Buitelaar Jan, Franke Barbara, de Jonge Maretha V, Bolton Patrick, Collier David, Curran Sarah, van Engeland Herman, van Ree Jan M
Abstract excerpt
BACKGROUND: The presence of specific and common genetic etiologies for autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) was investigated for 132 candidate genes in a two-stage design-association study. METHODS: 1,536 single nucleotide polymorphisms (SNPs) covering these candidate genes were tested in ASD (n = 144) and ADHD (n = 110) patients and control subjects (n = 404) from...
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