Article
A DRD1 haplotype is associated with risk for autism spectrum disorders in male-only affected sib-pair families.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2008
Hettinger Joe A, Liu Xudong, Schwartz Charles E, Michaelis Ron C, Holden Jeanette J A
Abstract excerpt
Individuals with autism spectrum disorders (ASDs) have impairments in executive function and social cognition, with males generally being more severely affected in these areas than females. Because the dopamine D1 receptor (encoded by DRD1) is integral to the neural circuitry mediating these proc...
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