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Article

An exploration of common dopaminergic variants and behavior problems in siblings at high risk for autism spectrum disorder.

Infant behavior & development - 1 Nov 2017

Gangi Devon N, Usher Lauren V, Messinger Daniel S

Abstract excerpt

Younger siblings of children with ASD often exhibit elevated internalizing and externalizing problems. We investigated common dopaminergic variants (DRD4 and DRD2) in relation to behavior problems at 36 months. Genotypes linked to less efficient dopaminergic functioning were associated with higher internalizing problems in high-risk siblings.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Dopamine D2

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Source

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Identifiers

PMID: 29054034
DOI: 10.1016/j.infbeh.2017.10.002
PMCID: PMC5716906

Genes

DRD2
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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