A preliminary study of dopamine D4 receptor genotype and structural brain alterations in adults with ADHD.

doi:10.1002/ajmg.b.30870

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Article

A preliminary study of dopamine D4 receptor genotype and structural brain alterations in adults with ADHD.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2008

Monuteaux Michael C, Seidman Larry J, Faraone Stephen V, Makris Nikos, Spencer Thomas, Valera Eve, Brown Ariel, Bush George, Doyle Alysa E, Hughes Samantha, Helliesen Meghan, Mick Eric, Biederman Joseph

Abstract excerpt

An emerging literature has demonstrated an association between the dopamine D4 receptor (DRD4) gene and volumetric brain abnormalities in children with ADHD. However, these results have not been extended to adults and have not addressed the impact of comorbidity. Our objective was to examine the DRD4 7R gene and volumetric brain abnormalities in adults with ADHD while accounting for comorbidity with bipolar...

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PMID: 18951431
DOI: 10.1002/ajmg.b.30870

Genes

DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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