Article
Deleterious impact of <i>Pseudomonas aeruginosa</i> on cystic fibrosis transmembrane conductance regulator function and rescue in airway epithelial cells
18 Mar 2015
Abstract excerpt
The epithelial response to bacterial airway infection, a common feature of lung diseases such as chronic obstructive pulmonary disease and cystic fibrosis, has been extensively studied. However, its impact on cystic fibrosis transmembrane conductance regulator (CFTR) channel function is not clearly defined. Our aims were, therefore, to evaluate the effect of Pseudomonas aeruginosa on CFTR function and expression...
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