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Interference of<i>Pseudomonas aeruginosa</i>signalling and biofilm formation for infection control

1 Apr 2010

Abstract excerpt

Pseudomonas aeruginosa is the best described bacterium with regards to quorum sensing (QS), in vitro biofilm formation and the development of antibiotic tolerance. Biofilms composed of P. aeruginosa are thought to be the underlying cause of many chronic infections, including those in wounds and in the lungs of patients with cystic fibrosis. In this review, we provide an overview of the molecular mechanisms...

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PMID: 20370936
DOI: 10.1017/s1462399410001420

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