Article

Reprogramming the cells secretory machinery: A cystic fibrosis rescue

2023-12-09

Abstract excerpt

<h4>ABSTRACT</h4> Cystic fibrosis (CF) is a genetic disorder resulting in the secretion of highly viscous mucus in the airways, leading to lung infection, respiratory failure, morbidity and mortality. CF is attributed to mutation in the CF Transmembrane Conductance Regulator (CFTR) gene that codes for a chloride transporting channel at the cell plasma membrane. More than 2,000 mutations in the CF gene have been i...

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Literature Corpus work: 96975a4d-f040-5869-9ded-6d5d47ab7bbd
DOI: 10.1101/2023.12.09.570886

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