Article
Retrospective study of the prevalence and clinical significance of hepatitis B virus precore and basal core promoter variants.
Canadian journal of gastroenterology & hepatology - 1 Jan 2000
O'Brien Meaghan, Casselman Adara, Smart Gerry, Gretchen Ainsley, Kaita Kelly, Kadkhoda Kamran
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) precore (PC) and basal core promoter (BCP) variants are well known; however, their prevalence in North America is unclear, especially among hepatitis B e antigen-negative patients. OBJECTIVE: To investigate the prevalence of PC⁄BCP mutations and their clinical significance. METHODS: One hundred twenty-eight patients positive for both hepatitis B surface antigen and hepatitis B...
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