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Article

Cyclin A1 regulates the interactions between mouse haematopoietic stem and progenitor cells and their niches.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Miftakhova Regina, Hedblom Andreas, Batkiewicz Leah, Anagnosaki Lola, Zhang Yuan, Sjölander Anita, Wingren Anette Gjörloff, Wolgemuth Debra J, Persson Jenny L

Abstract excerpt

It remains poorly understood how the haematopoietic stem/progenitor cells (HSPC) are attracted to their niches and the functional consequences of such interaction. In the present study, we show that the cell cycle regulator cyclin A1 in association with vascular endothelial growth factor receptor 1 (VEGFR1), is required for HSPC and their niches to maintain their function and proper interaction. In the absence of...

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Identifiers

PMID: 25785996
DOI: 10.1080/15384101.2015.1026513
PMCID: PMC4614519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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