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Article

Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders.

Psychoneuroendocrinology - 1 Nov 2023

Hindley Guy, Drange Ole Kristian, Lin Aihua, Kutrolli Gleda, Shadrin Alexey A, Parker Nadine, O'Connell Kevin S, Rødevand Linn, Cheng Weiqiu, Bahrami Shahram, Karadag Naz, Holen Børge, Jaholkowski Piotr, Woldeyohannes Markos Tesfaye, Djurovic Srdjan, Dale Anders M, Frei Oleksandr, Ueland Thor, Smeland Olav B, Andreassen Ole A

Abstract excerpt

C-reactive protein (CRP) tends to be elevated in individuals with psychiatric disorders. Recent findings have suggested a protective effect of the genetic liability to elevated CRP on schizophrenia risk and a causative effect on depression despite weak genetic correlations, while causal relationships with bipolar disorder were inconclusive. We investigated the shared genetic underpinnings of psychiatric disorders...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37659117
DOI: 10.1016/j.psyneuen.2023.106368
PMCID: PMC10802833

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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