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Article

Genome-wide association study in two populations to determine genetic variants associated with Toxoplasma gondii infection and relationship to schizophrenia risk.

Progress in neuro-psychopharmacology & biological psychiatry - 8 Jun 2019

Wang Alex W, Avramopoulos Dimitrios, Lori Adriana, Mulle Jennifer, Conneely Karen, Powers Abigail, Duncan Erica, Almli Lynn, Massa Nicholas, McGrath John, Schwartz Ann C, Goes Fernando S, Weng Lei, Wang Ruihua, Yolken Robert, Ruczinski Ingo, Gillespie Charles F, Jovanovic Tanja, Ressler Kerry, Pulver Ann E, Pearce Brad D

Abstract excerpt

T. gondii (TOXO) infects over one billion people worldwide, yet the literature lacks a Genome Wide Association Study (GWAS) focused on genetic variants controlling the persistence of TOXO infection. To identify putative T. gondii susceptibility genes, we performed a GWAS using IgG seropositivity as the outcome variable in a discovery sample (n = 790) from an Ashkenazi dataset, and a second sample of predominately...

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Antibodies, Protozoan
Black or African American
Cohort Studies
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoglobulin G

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Open in PubMed Open full text

Identifiers

PMID: 30610941
DOI: 10.1016/j.pnpbp.2018.12.019
PMCID: PMC12854273

Genes

CD44
RXRA
CHIA
CNTNAP2
NOTCH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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