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Article

Joint evaluation of serum C-Reactive Protein levels and polygenic risk scores as risk factors for schizophrenia.

Psychiatry research - 1 Mar 2018

Nimgaonkar Vishwajit L, Dickerson Faith, Pouget Jennie G, Chowdari Kodavali, O'Dushlaine Colm, Wood Joel, Klei Lambertus, Devlin Bernie, Yolken Robert

Abstract excerpt

Several studies have indicated infectious and immune-related abnormalities in schizophrenia (Scz), including elevated serum C-reactive protein (CRP) - a well-known proxy for infections/immune abnormalities. A portion of the genetic risk for Scz can be estimated using the polygenic risk score (PGRS). It is not known whether there is an interaction in the risks traceable to CRP and PGRS. Patients with Scz and...

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Identifiers

PMID: 29306175
DOI: 10.1016/j.psychres.2017.12.025
PMCID: PMC6941903

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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