Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic Host Cell Alterations in HPV Carcinogenesis.

Viruses - 3 Aug 2017

Litwin Tamara R, Clarke Megan A, Dean Michael, Wentzensen Nicolas

Abstract excerpt

High-risk human papilloma virus (HPV) infections cause cancers in different organ sites, most commonly cervical and head and neck cancers. While carcinogenesis is initiated by two viral oncoproteins, E6 and E7, increasing evidence shows the importance of specific somatic events in host cells for malignant transformation. HPV-driven cancers share characteristic somatic changes, including apolipoprotein B mRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Receptor, Notch1
Share to APOBEC Deaminases
Share to Carcinogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Viral

Share to Class I Phosphatidylinositol 3-Kinases

Share to Head and Neck Neoplasms

Share to Oncogene Proteins, Viral

Share to PTEN Phosphohydrolase

Source

Open in PubMed Open full text

Identifiers

PMID: 28771191
DOI: 10.3390/v9080206
PMCID: PMC5580463

Genes

NOTCH1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic Host Cell Alterations in HPV Carcinogenesis.PMID 28771191Read ↗

HPV-driven oncogenesis—much more than the E6 and E7 oncoproteinsSemantic proximity Read ↗

Genomic Landscape of Human Papillomavirus–Associated CancersSemantic proximity Read ↗

Molecular pathways in the development of HPV-induced oropharyngeal cancerSemantic proximity Read ↗

Human malignancies associated with persistent HPV infectionSemantic proximity Read ↗

Molecular Insights into HPV-Driven Head and Neck Cancers: From Viral Oncoproteins to Precision TherapeuticsSemantic proximity Read ↗

APOBEC Mutagenesis is Concordant Between Tumor and Viral Genomes in HPV Positive Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Genomic Instability and DNA Damage Repair Pathways Induced by Human Papillomaviruses.Semantic proximity Read ↗

APOBEC-mediated genomic alterations link immunity and viral infection during human papillomavirus-driven cervical carcinogenesisSemantic proximity Read ↗

Molecular events in the pathogenesis of vulvar squamous cell carcinoma.Semantic proximity Read ↗

Human papillomavirus genomics: Understanding carcinogenicitySemantic proximity Read ↗

Hallmarks of HPV carcinogenesis: The role of E6, E7 and E5 oncoproteins in cellular malignancySemantic proximity Read ↗

The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.