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Article

Molecular pathways in the development of HPV-induced oropharyngeal cancer

14 Dec 2023

Abstract excerpt

Oropharyngeal cancer, a subset of head and neck cancer, is increasingly recognized as a unique clinical entity primarily influenced by high-risk human papillomavirus (HPV) infections, particularly HPV-16. This review delves into the viral life cycle of HPV-16 and its interactions with host cells, with a specific focus on the crucial roles played by the viral oncoproteins E6 and E7. These oncoproteins drive...

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PMID: 38098017
DOI: 10.1186/s12964-023-01365-0

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