Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of the anti-inflammatory IL-10 gene associated with malignancy in female reproductive system.

Bulletin of experimental biology and medicine - 1 Mar 2015

Tuguz A R, Anokhina E N, Muzhenya D V, Rudenko K A

Abstract excerpt

Association of three polymorphisms (1082G/A, 819C/T, and 592C/A) of the promotor region of the anti-inflammatory IL-10 gene with malignancy of female reproductive organs was revealed by SNP (single nucleotide polymorphism) method in ethnic groups of Adygei Republic. Breast cancer, cervical cancer, and cancer of the uterine corpus are associated with allele 592A (р=0.042) in Circassians and with polymorphism 819T...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Gene Frequency
Share to Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-10

Share to Polymorphism, Genetic

Share to Risk Factors

Share to Uterine Cervical Neoplasms

Share to White People

Source

Identifiers

PMID: 25778657
DOI: 10.1007/s10517-015-2832-x

Genes

GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of the anti-inflammatory IL-10 gene associated with malignancy in female reproductive system.PMID 25778657Read ↗

IL-10 c.-592C>A (rs1800872) polymorphism is associated with cervical cancer.Semantic proximity Read ↗

The association between interleukin-10 (IL-10) -592C/A, -819T/C, -1082G/A promoter polymorphisms and endometriosis.Semantic proximity Read ↗

Significance of -1082A/G polymorphism of IL10 gene for progression of colorectal cancer and IL-10 expression.Semantic proximity Read ↗

Inflammatory breast cancer: High incidence of GCC haplotypes (-1082A/G, -819T/C, and -592A/C) in the interleukin-10 gene promoter correlates with over-expression of interleukin-10 in patients' carcinoma tissues.Semantic proximity Read ↗

The interleukin-10 (-1082A/G) polymorphism is strongly associated with increased risk for oral squamous cell carcinoma.Semantic proximity Read ↗

Association of TNFA (-308G>A) and IL-10 (-819C>T) promoter polymorphisms with risk of cervical cancer.Semantic proximity Read ↗

Interleukin-10 -592C/A, but not -1082A/G promoter single nucleotide polymorphism, is associated with a decreased risk of colorectal cancer in an ethnic Kashmiri population: a case-control study.Semantic proximity Read ↗

Association of a genetic variant in Interleukin-10 gene with increased risk and inflammation associated with cervical cancer.Semantic proximity Read ↗

Interleukin 10 rs1800896 and interleukin 1B rs16944 polymorphisms and the risk of cervical cancer.Semantic proximity Read ↗

A functional role of the SNP -592 of human IL10 gene regulatory region is associated with an increased IL-10 expression and risk for human papillomavirus cervical lesion and cervical cancer developmentSemantic proximity Read ↗

Association of IL-10 GTC haplotype with serum level and HPV infection in the development of cervical carcinoma.Semantic proximity Read ↗

Interleukin-10 G-1082A and C-819T polymorphisms as possible molecular markers of urothelial bladder cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.