Association of TNFA (-308G>A) and IL-10 (-819C>T) promoter polymorphisms with risk of cervical cancer.

doi:10.1111/IGC.0b013e3181a3a3af

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Article

Association of TNFA (-308G>A) and IL-10 (-819C>T) promoter polymorphisms with risk of cervical cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Oct 2009

Singh HariOm, Jain Meenu, Sachan Rekha, Mittal Balraj

Abstract excerpt

Etiology of cervical cancer is associated with excessive inflammation mediated tumorigenesis. Pro and anti-inflammatory cytokines (tumor necrosis factor alpha, TNFA and interleukin, IL-10) are involved in fighting against the tumorigenesis. Therefore, the present study was designed to evaluate the association of TNFA (-308G>A) and IL-10 (-819C>T) gene polymorphism with risk of cervical cancer. One hundred fifty...

Topics

Adult
Carcinoma
DNA Mutational Analysis
Environment
Female
Genetic Linkage
Genetic Predisposition to Disease
Humans
Interleukin-10
Middle Aged
Neoplasm Staging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Risk Factors

Tumor Necrosis Factor-alpha

Uterine Cervical Neoplasms

Source

Open in PubMed

Identifiers

PMID: 19823053
DOI: 10.1111/IGC.0b013e3181a3a3af

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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