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Article

Genome-wide gene pathway analysis of psychotic illness symptom dimensions based on a new schizophrenia-specific model of the OPCRIT.

Schizophrenia research - 1 May 2015

Docherty Anna R, Bigdeli T Bernard, Edwards Alexis C, Bacanu Silviu, Lee Donghyung, Neale Michael C, Wormley Brandon K, Walsh Dermot, O'Neill F Anthony, Riley Brien P, Kendler Kenneth S, Fanous Ayman H

Abstract excerpt

Empirically derived phenotypic measurements have the potential to enhance gene-finding efforts in schizophrenia. Previous research based on factor analyses of symptoms has typically included schizoaffective cases. Deriving factor loadings from analysis of only narrowly defined schizophrenia cases could yield more sensitive factor scores for gene pathway and gene ontology analyses. Using an Irish family sample,...

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Identifiers

PMID: 25778617
DOI: 10.1016/j.schres.2015.02.013
PMCID: PMC4409533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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