Article
A data-driven investigation of relationships between bipolar psychotic symptoms and schizophrenia genome-wide significant genetic loci.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2018
Leonenko Ganna, Di Florio Arianna, Allardyce Judith, Forty Liz, Knott Sarah, Jones Lisa, Gordon-Smith Katherine, Owen Michael J, Jones Ian, Walters James, Craddock Nick, O'Donovan Michael C, Escott-Price Valentina
Abstract excerpt
The etiologies of bipolar disorder (BD) and schizophrenia include a large number of common risk alleles, many of which are shared across the disorders. BD is clinically heterogeneous and it has been postulated that the pattern of symptoms is in part determined by the particular risk alleles carried, and in particular, that risk alleles also confer liability to schizophrenia influence psychotic symptoms in those...
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