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Article

Genetic modifiers of response to glucose-insulin-potassium (GIK) infusion in acute coronary syndromes and associations with clinical outcomes in the IMMEDIATE trial.

The pharmacogenomics journal - 1 Dec 2015

Ellis K L, Zhou Y, Beshansky J R, Ainehsazan E, Selker H P, Cupples L A, Huggins G S, Peter I

Abstract excerpt

Modifiers of response to glucose, insulin and potassium (GIK) infusion may affect clinical outcomes in acute coronary syndromes (ACS). In an Immediate Myocardial Metabolic Enhancement During Initial Assessment And Treatment In Emergency Care (IMMEDIATE) trial's sub-study (n = 318), we explored effects of 132,634 genetic variants on plasma glucose and potassium response to 12-h GIK infusion. Associations between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25778467
DOI: 10.1038/tpj.2015.10
PMCID: PMC4573824

Genes

ABCB11
ACSL1
ADCYAP1
AHCYL1
AKAP12
ARFGEF2
CSF1
DNAH5
LCA5
MAGI1
NDRG4
PTPRG
SETX
STRADA
XPO4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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