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Article

Nonfasting glucose, ischemic heart disease, and myocardial infarction: a Mendelian randomization study.

Journal of the American College of Cardiology - 19 Jun 2012

Benn Marianne, Tybjaerg-Hansen Anne, McCarthy Mark I, Jensen Gorm B, Grande Peer, Nordestgaard Børge G

Abstract excerpt

OBJECTIVES: The purpose of this study was to test whether elevated nonfasting glucose levels associate with and cause ischemic heart disease (IHD) and myocardial infarction (MI). BACKGROUND: Elevated fasting plasma glucose levels associate with increased risk of IHD, but whether this is also true for nonfasting levels and whether this is a causal relationship is unknown. METHODS: Using a Mendelian randomization...

Topics

Adult
Aged
Alleles
Blood Glucose
Body Mass Index
Cholesterol, HDL
Denmark
Female
Genotype
Humans
Hypertension
Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mendelian Randomization Analysis

Middle Aged

Myocardial Infarction

Myocardial Ischemia

Odds Ratio

Source

Open in PubMed Open full text

Identifiers

PMID: 22698489
DOI: 10.1016/j.jacc.2012.02.043
PMCID: PMC4606982

Genes

ADCY5
DGKB
GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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