Article

Acute pharmacodynamic responses to exenatide: Drug-induced increases in insulin secretion and glucose effectiveness

2023-03-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> GLP1R agonists provide multiple benefits to patients with type 2 diabetes – including improved glycemic control, weight loss, and decreased risk of major adverse cardiovascular events. Because drug responses vary among individuals, we initiated investigations to identify genetic variants associated with the magnitude of drug responses. <h4>Methods</h4> Exenatide (5 µg, sc) or...

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Literature Corpus work: 531f8f00-2037-5fd6-a1a3-711d233964d0
DOI: 10.1101/2023.03.15.23287166

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