Article
Murine models of systemic lupus erythematosus.
Journal of biomedicine & biotechnology - 1 Jan 2011
Perry Daniel, Sang Allison, Yin Yiming, Zheng Ying-Yi, Morel Laurence
Abstract excerpt
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disorder. The study of diverse mouse models of lupus has provided clues to the etiology of SLE. Spontaneous mouse models of lupus have led to identification of numerous susceptibility loci from which several candidate genes have emerged. Meanwhile, induced models of lupus have provided insight into the role of environmental factors in lupus...
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