Animal Models of Lupus Nephritis: Current Status and Future Perspectives.

Abstract excerpt

Lupus nephritis (LN) represents one of the most severe complications associated with systemic lupus erythematosus (SLE) characterized by a complex pathogenesis. Animal models play a pivotal role in elucidating the pathogenesis of LN, facilitating drug discovery, and evaluating therapeutic interventions. A diverse array of LN animal models is currently employed in research. Concurrently, the evaluation of these...

Topics

• Animals
• Lupus Nephritis
• Disease Models, Animal
• Humans
• Phenotype
• Kidney