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Article

Somatic mutations in myeloid cell leukemia-1 contribute to the pathogenesis of glioma by prolonging its half-life.

Molecular medicine reports - 1 Jul 2015

Lv Xiupeng, Tan Guang, Yao Yiqun, Lv Li, Deng Xiaoqin, Dong Lei, Li Shuang, Li Linlin, Xu Yinghui

Abstract excerpt

The identification of mutated genes in glioblastoma multiforme (GBM) is an essential step towards improving current understanding of the molecular mechanism underlying the disease and establishing novel targets for diagnostic and therapeutic purposes. The present study used direct sequencing to screen 20 malignancy-associated genes, which have either been well described in the literature or observed multiple...

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PMID: 25777305
DOI: 10.3892/mmr.2015.3493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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