Article
Acyl-CoA oxidase complexes control the chemical message produced by Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America - 31 Mar 2015
Zhang Xinxing, Feng Likui, Chinta Satya, Singh Prashant, Wang Yuting, Nunnery Joshawna K, Butcher Rebecca A
Abstract excerpt
Caenorhabditis elegans uses ascaroside pheromones to induce development of the stress-resistant dauer larval stage and to coordinate various behaviors. Peroxisomal β-oxidation cycles are required for the biosynthesis of the fatty acid-derived side chains of the ascarosides. Here we show that three acyl-CoA oxidases, which catalyze the first step in these β-oxidation cycles, form different protein homo- and...
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