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Article

Caenorhabditis elegans utilizes dauer pheromone biosynthesis to dispose of toxic peroxisomal fatty acids for cellular homoeostasis.

The Biochemical journal - 29 Jul 2009

Joo Hyoe-Jin, Yim Yong-Hyeon, Jeong Pan-Young, Jin You-Xun, Lee Jeong-Eui, Kim Heekyeong, Jeong Seul-Ki, Chitwood David J, Paik Young-Ki

Abstract excerpt

Caenorhabditis elegans excretes a dauer pheromone or daumone composed of ascarylose and a fatty acid side chain, the perception of which enables worms to enter the dauer state for long-term survival in an adverse environment. During the course of elucidation of the daumone biosynthetic pathway in which DHS-28 and DAF-22 are involved in peroxisomal beta-oxidation of VLCFAs (very long-chain fatty acids), we sought...

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PMID: 19496754
DOI: 10.1042/BJ20090513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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