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Article

A shortcut to identifying small molecule signals that regulate behavior and development in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 12 May 2009

Pungaliya Chirag, Srinivasan Jagan, Fox Bennett W, Malik Rabia U, Ludewig Andreas H, Sternberg Paul W, Schroeder Frank C

Abstract excerpt

Small molecule metabolites play important roles in Caenorhabditis elegans biology, but effective approaches for identifying their chemical structures are lacking. Recent studies revealed that a family of glycosides, the ascarosides, differentially regulate C. elegans development and behavior. Low concentrations of ascarosides attract males and thus appear to be part of the C. elegans sex pheromone, whereas higher...

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Identifiers

PMID: 19346493
DOI: 10.1073/pnas.0811918106
PMCID: PMC2683085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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