Article
A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains.
G3 (Bethesda, Md.) - 13 Mar 2015
Andersen Erik C, Shimko Tyler C, Crissman Jonathan R, Ghosh Rajarshi, Bloom Joshua S, Seidel Hannah S, Gerke Justin P, Kruglyak Leonid
Abstract excerpt
The genetic variants underlying complex traits are often elusive even in powerful model organisms such as Caenorhabditis elegans with controlled genetic backgrounds and environmental conditions. Two major contributing factors are: (1) the lack of statistical power from measuring the phenotypes of small numbers of individuals, and (2) the use of phenotyping platforms that do not scale to hundreds of individuals...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.