Article
A spontaneous complex structural variant in rcan-1 increases exploratory behavior and laboratory fitness of Caenorhabditis elegans.
PLoS genetics - 1 Feb 2020
Zhao Yuehui, Long Lijiang, Wan Jason, Biliya Shweta, Brady Shannon C, Lee Daehan, Ojemakinde Akinade, Andersen Erik C, Vannberg Fredrik O, Lu Hang, McGrath Patrick T
Abstract excerpt
Over long evolutionary timescales, major changes to the copy number, function, and genomic organization of genes occur, however, our understanding of the individual mutational events responsible for these changes is lacking. In this report, we study the genetic basis of adaptation of two strains of C. elegans to laboratory food sources using competition experiments on a panel of 89 recombinant inbred lines (RIL)....
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