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Article

Evaluating the power and limitations of genome-wide association studies in Caenorhabditis elegans.

G3 (Bethesda, Md.) - 6 Jul 2022

Widmayer Samuel J, Evans Kathryn S, Zdraljevic Stefan, Andersen Erik C

Abstract excerpt

Quantitative genetics in Caenorhabditis elegans seeks to identify naturally segregating genetic variants that underlie complex traits. Genome-wide association studies scan the genome for individual genetic variants that are significantly correlated with phenotypic variation in a population, or quantitative trait loci. Genome-wide association studies are a popular choice for quantitative genetic analyses because...

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PMID: 35536194
DOI: 10.1093/g3journal/jkac114
PMCID: PMC9258552

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