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Article

Haploidentical hematopoietic transplantation from KIR ligand-mismatched donors with activating KIRs reduces nonrelapse mortality.

Blood - 14 May 2015

Mancusi Antonella, Ruggeri Loredana, Urbani Elena, Pierini Antonio, Massei Maria Speranza, Carotti Alessandra, Terenzi Adelmo, Falzetti Franca, Tosti Antonella, Topini Fabiana, Bozza Silvia, Romani Luigina, Tognellini Rita, Stern Martin, Aversa Franco, Martelli Massimo F, Velardi Andrea

Abstract excerpt

Because activating killer cell immunoglobulinlike receptors (KIRs) are heterogeneously expressed in the population, we investigated the role of donor activating KIRs in haploidentical hematopoietic transplants for acute leukemia. Transplants were grouped according to presence vs absence of KIR-ligand mismatches in the graft-vs-host direction (ie, of donor-vs-recipient natural killer [NK]-cell alloreactivity). In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25769621
DOI: 10.1182/blood-2014-09-599993

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Haploidentical hematopoietic transplantation from KIR ligand-mismatched donors with activating KIRs reduces nonrelapse mortality.PMID 25769621Read ↗

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