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Article

Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors.

European journal of immunology - 1 Jun 2015

Akeus Paulina, Langenes Veronica, Kristensen Jonas, von Mentzer Astrid, Sparwasser Tim, Raghavan Sukanya, Quiding-Järbrink Marianne

Abstract excerpt

Colorectal cancer (CRC) is one of the most prevalent tumor types worldwide and tumor-infiltrating T cells are crucial for anti-tumor immunity. We previously demonstrated that Treg cells from CRC patients inhibit transendothelial migration of conventional T cells. However, it remains unclear if lo...

Read the complete abstract on PubMed

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Share to Adenomatous Polyposis Coli Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Chemokine

Share to Receptors, CXCR3

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Source

Identifiers

PMID: 25754875
DOI: 10.1002/eji.201445058

Genes

CXCR3
APC
CXCL10
CXCL9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25754875-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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