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Article

Ikaros and leukaemia.

British journal of haematology - 1 May 2015

Olsson Linda, Johansson Bertil

Abstract excerpt

The IKZF1 gene at 7p12.2 codes for IKAROS (also termed IKZF1), an essential transcription factor in haematopoiesis involved primarily in lymphoid differentiation. Its importance is underlined by the fact that deregulation of IKAROS results in leukaemia in both mice and men. During recent years, constitutional as well as acquired genetic changes of IKZF1 have been associated with human disease. For example,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Share to Receptors, Cytokine

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Share to Transcriptional Regulator ERG

Source

Identifiers

PMID: 25753742
DOI: 10.1111/bjh.13342

Genes

IKZF1
CRLF2
ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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